Printability during projection-based 3D bioprinting

• DOI: 10.1016/j.bioactmat.2021.09.021
• Publication Date: 2021-09-21T04:56:20Z
• Authors: Kang Yu; Xinjie Zhang; Yuan Sun; Qing Gao; Jianzhong Fu; Xiujun Cai; Yong He
• Keywords: Gelatin; 3D bioprinting

Since projection-based 3D bioprinting (PBP) could provide high resolution, it is well suited for printing delicate structures tissue regeneration. However, the low crosslinking density and photo-crosslinking rate of photocurable bioink make difficult to print fine structures. Currently, an in-depth understanding lacking. Here, a research framework established analysis printability during PBP. The gelatin methacryloyl (GelMA)-based used as example, systematically investigated. We analyze reactions PBP process summarize specific requirements bioinks Two standard quantized models are evaluate 2D errors. Finally, better strategies five typical structures, including solid organs, vascular nerve conduits, thin-wall scaffolds, micro needles, presented.