Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study
Male
paediatric
Time Factors
morbidity
Severity of Illness Index
0302 clinical medicine
Risk Factors
info:eu-repo/classification/ddc/617
Age Factor
Anesthesia
Prospective Studies
Hypoxia
Medical Audit
ddc:617
airways; anaesthesia; difficult intubation; infants; morbidity; mortality; neonates; paediatric.
infants
Incidence
Age Factors
anaesthesia
3. Good health
Europe
Treatment Outcome
Female
Human
Time Factor
610 Medicine & health
Anesthesia/adverse effects/mortality
Risk Assessment
Europe/epidemiology
Laryngoscopy/adverse effects/mortality
03 medical and health sciences
Hypoxia/diagnosis/epidemiology/mortality
Intubation, Intratracheal
difficult intubation
Humans
Laryngoscopy
Risk Factor
Infant, Newborn
Infant
Newborn
infant
mortality
neonates
Intratracheal
Prospective Studie
airway
Intubation, Intratracheal/adverse effects/mortality
neonate
Intubation
airways
DOI:
10.1016/j.bja.2021.02.021
Publication Date:
2021-04-01T06:01:43Z
AUTHORS (506)
ABSTRACT
Neonates and infants are susceptible to hypoxaemia in the perioperative period. The aim of this study was analyse interventions related anaesthesia tracheal intubations European cohort identify their clinical consequences.We performed a secondary analysis multicentre observational trial (NEonate Children audiT Anaesthesia pRactice IN Europe [NECTARINE]) neonates small with difficult intubation. primary endpoint incidence intubation complications. endpoints were risk factors for severe attributed airway management, 30 90 day outcomes.Tracheal planned 4683 procedures. Difficult intubation, defined as two failed attempts direct laryngoscopy, occurred 266 children (271 procedures) an (95% confidence interval [CI]) 5.8% CI, 5.1-6.5). Bradycardia 8% cases whereas significant decrease oxygen saturation (SpO2<90% 60 s) reported 40%. No associated could be identified among co-morbidities, surgical, or management. Using propensity scoring adjust confounders, did not lead increase morbidity mortality.The results present demonstrate high less than weeks post-conceptual age commonly resulting hypoxaemia. Reassuringly, mortality at days increased by occurrence event.NCT02350348.
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