Unraveling the transcriptome profile of pulsed electromagnetic field stimulation in bone regeneration using a bioreactor-based investigation platform

• DOI: 10.1016/j.bone.2024.117065
• Publication Date: 2024-02-28T11:41:36Z
• Authors: Farah Daou; Beatrice Masante; Stefano Gabetti; Federico Mochi; Giovanni Putame; Eleonora Zenobi; Elisa Scatena; Federica Dell'Atti; Francesco Favero; Massimiliano Leigheb; Costantino Del Ga...; Cristina Bignardi; Diana Massai; Andrea Cochis; Lia Rimondini
• Keywords: Regenerative Medicine

Human mesenchymal stem cells (hMSCs) sense and respond to biomechanical biophysical stimuli, yet the involved signaling pathways are not fully identified. The clinical application of stimulation including pulsed electromagnetic field (PEMF) has gained momentum in musculoskeletal disorders bone tissue engineering.