Multiple Stressors Induce Amygdalohippocampal Volume Reduction in Adult Male Rats as Detected by Longitudinal Structural Magnetic Resonance Imaging

• DOI: 10.1016/j.bpsgos.2024.100334
• Publication Date: 2024-05-15T06:45:58Z
• Authors: Rie Ryoke; Teruo Hashimoto; Ryuta Kawashima
• Keywords: Psychiatry; Archival Report; 03 medical and health sciences; Magnetic resonance imaging; 0302 clinical medicine; RC435-571; Posttraumatic stress disorder; Individual variability; Amygdala; Hippocampus

Traumatic events can cause long-lasting and uncontrollable fear anxiety. Posttraumatic stress disorder is an intractable mental disorder, neurobiological mechanisms using animal models are expected to help development of posttraumatic treatment. In this study, we combined multiple (MS) longitudinal in vivo magnetic resonance imaging reveal the effects anxiety-like behaviors on adult male rat brains.