Ultra-rapid regrowth of urothelial cardiac metastasis after debulking surgery

• DOI: 10.1016/j.carpath.2021.107334
• Publication Date: 2021-03-20T04:25:41Z
• Authors: Chiara Zanchettin; Luca Zanella; Giampaolo Zoffoli; Andrea Venturini; Alan Gallingani; Federico Ronco; Cristina Basso; Stefania Rizzo; Domenico Mangino
• Keywords: Debulking; Urothelial cancer

Cardiac metastases of urothelial carcinoma are a rare manifestation, and most of them are asymptomatic or autoptic findings. We report a case of a 64-year-old Caucasian man fully asymptomatic, who has been accidentally diagnosed with a right atrial mass during his routine follow up for previous urothelial cancer. Endomyocardial biopsy, and histological examination of the mass were crucial to reach a definitive diagnosis of urothelial metastasis. He underwent a debulking surgery of the mass to avoid cardiac life-threatening complications. Despite effective removal of the atrial metastasis, after 45 days the patient experienced an ultra-rapid regrowth of the mass in the same position. This case demonstrates how rapidly a urothelial cardiac metastasis can grow back, and that surgery does not avoid by itself early recurrence.