The impact of formaldehyde exposure on lung inflammatory disorders: Insights into asthma, bronchitis, and pulmonary fibrosis

• DOI: 10.1016/j.cbi.2024.111002
• Publication Date: 2024-04-09T15:52:26Z
• Authors: Asif Ahmad Bhat; Muhammad Afzal; Ahsas Goyal; Gaurav Gupta; Riya Thapa; Waleed Hassan alm...; Imran Kazmi; Sami I. Alzarea; Moyad Shahwan; Keshav Raj Paudel; Haider Ali; Dipak Sahu; Parteek Prasher; Sachin Kumar Singh; Kamal Dua
• Keywords: Hypersensitivity pneumonitis; Chronic bronchitis; Respiratory tract; Aggravating Factor

Lung inflammatory disorders are a major global health burden, impacting millions of people and raising rates morbidity death across many demographic groups. An industrial chemical common environmental contaminant, formaldehyde (FA) presents serious concerns to the respiratory system, including onset aggravation lung disorders. Epidemiological studies have shown significant associations between FA exposure levels incidence severity several diseases. causes inflammation in tract via immunological activation, oxidative stress, airway remodelling, aggravating pre-existing pulmonary compromising function. Additionally, functions as sensitizer, causing allergic responses hypersensitivity pneumonitis sensitive people. Understanding complicated processes behind formaldehyde-induced is critical for directing targeted strategies aimed at minimizing exposures alleviating burden formaldehyde-related illnesses on health. This abstract explores intricate relationship diseases, asthma, bronchitis, inflammation, injury fibrosis.