Exposure to aluminum, aluminum + manganese and acid pH triggers different antioxidant responses in gills and liver of Astyanax altiparanae (Teleostei: Characiformes: Characidae) males

• DOI: 10.1016/j.cbpc.2018.09.004
• Publication Date: 2018-10-11T05:24:47Z
• Authors: R.P. Abdalla; B.M.S. Kida; J.P.S. Pinheiro; L.F. Oliveira; C.B.F. Martinez; R.G. Moreira
• Keywords: Characiformes; Metallothionein

Exposure to aluminum (Al) and + manganese (Mn) can trigger an increase in reactive oxygen species (ROS) modify the activity of oxidative defense enzymes. This study investigated whether exposure Al Mn at acid pH for 24 96 h causes stress evidenced by antioxidants damage gills liver sexually mature Astyanax altiparanae males. The fish were subsequently immersed metal-free water see they recovered from effects these metals. boosted gill superoxide dismutase (SOD) did not recover when same period neutral pH. increased glutathione (GSH) levels (24 h) gills, returning control during recovery period, showing efficiency antioxidant system preventing lipid peroxidation liver. enzymes studied, but late hepatic period. group exposed exhibited several alterations, including concentration GSH, as well higher GPx GR gills. Despite defensive responses triggered acute exposure, there alterations catalase (96 metallothionein h), this prevent peroxidation. produced different effects, timing enzymatic non-enzymatic defenses also differed.