Study protocol for a randomized, placebo-controlled, double-masked mechanistic clinical trial of transdermal estrogen replacement in hypoestrogenic eating disorders to explore the role of estrogen on cognitive flexibility and reward processing

• DOI: 10.1016/j.cct.2025.107924
• Publication Date: 2025-04-26T22:33:46Z
• Authors: Lauren Breithaupt; Meghan Slattery; Meghan Lauze; Felicia Petterway; Lauren Lindman; Mia Cravitz; Sarah Naticchia; Siddarth Seenivasa; Macy Powers; Kristin N. Javaras; David J. Alperovitz; Judith Halperin; Esther Dechant; Jennifer J. Thomas; Elizabeth A. Lawson; Hang Lee; Diego A. Pizzagalli; Adrienne L. Romer; Poornima Kumar; Franziska Plessow; Madhusmita Misra; Kamryn T. Eddy
• Keywords: Estrogen replacement therapy; Cognitive flexibility