A reduced graphene oxide-Fe3O4 composite functionalized with cetyltrimethylammonium bromide for efficient adsorption of SARS-CoV-2 spike pseudovirus and human enteric viruses

• DOI: 10.1016/j.chemosphere.2021.132995
• Publication Date: 2021-11-19T07:28:58Z
• Authors: Shuqing Zhou; Min Jin; Rong Tan; Zhiqiang Shen; Jing Yin; Zhigang Qiu; Zhengshan Chen; Danyang Shi; Haibei Li; Zhongwei Yang; Huaran Wang; Zhixian Gao; Junwen Li; Dong Yang
• Keywords: 0303 health sciences; 03 medical and health sciences; Cetrimonium; SARS-CoV-2; COVID-19; Humans; Graphite; Adsorption; Article; 3. Good health

The latent dangers of waterborne viral transmission have become a major public health concern. In this study, reduced graphene oxide (rGO)-Fe3O4 nanoparticles were decorated with cetyltrimethylammonium bromide (CTAB) to adsorb severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike pseudovirus and three human enteric viruses (HuNoV, HRV, HAdV). successful combination CTAB rGO-Fe3O4 was confirmed by electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, zeta potential, Brunner-Emmet-Teller, vibrating sample magnetometer measurements. adsorption HuNoV HAdV followed pseudo-first-order kinetics, while that HRV conformed the pseudo-second-order model. CTAB-functionalized exhibited exceptionally high HuNoV, SARS-CoV-2 pseudovirus, maximum capacities 3.55 × 107, 7.01 2.21 107 6.92 106 genome copies mg-1, respectively. Moreover, composite could effectively four types virus particles from coastal, tap, river water. addition, concentrating virions using functionalized composites before qPCR analysis significantly improved detection limit. results indicate are captured on surface through electrostatic interactions intrinsic ability rGO. Overall, promising materials for as well complex aqueous environments.