Trehalose: A sugar molecule involved in temperature stress management in plants

• DOI: 10.1016/j.cj.2023.09.010
• Publication Date: 2023-10-29T09:31:50Z
• Authors: Ali Raza; Savita Bhardwaj; Md Atikur Rahman; Pedro García-Capa...; Madiha Habib; Faisal Saeed; Sidra Charagh; Christine H. Foyer; Kadambot H.M. Sid...; Rajeev K. Varshney
• Keywords: 0303 health sciences; 03 medical and health sciences; Osmolyte; S; Agriculture (General); Genetic engineering; Agriculture; Gene expression; Abiotic stress; Trehalose-6-phosphate; S1-972

Trehalose (Tre) is a non-reducing disaccharide found in many species, including bacteria, fungi, invertebrates, yeast, and even plants, where it acts as an osmoprotectant, energy source, or protein/membrane protector. Despite relatively small amounts Tre concentrations increase following exposure to abiotic stressors. Trehalose-6-phosphate, precursor of Tre, has regulatory functions sugar metabolism, crop production, stress tolerance. Among the various stresses, temperature extremes (heat cold stress) are anticipated impact production worldwide due ongoing climate changes. Applying can mitigate negative physiological, metabolic, molecular responses triggered by stress. also interacts with other sugars, osmoprotectants, amino acids, phytohormones regulate metabolic reprogramming that underpins adaptation. Transformed plants expressing Tre-synthesis genes accumulate show improved Genome-wide studies Tre-encoding suggest roles plant growth, development, This review discusses mitigating stress—highlighting genetic engineering approaches modify crosstalk, interactions molecules—and in-silico for identifying novel diverse species. We consider how this knowledge be used develop temperature-resilient crops essential sustainable agriculture.