Multiscale neuro-inspired models for interpretation of EEG signals in patients with epilepsy

• DOI: 10.1016/j.clinph.2024.03.006
• Publication Date: 2024-03-16T06:04:25Z
• Authors: Fabrice Wendling; Elif Koksal-Ersoz; Mariam Al-Harrach; Maxime Yochum; Isabelle Merlet; Giulio Ruffini; Fabrice Bartolomei; Pascal Benquet
• Keywords: [SDV.IB] Life Sciences [q-bio]/Bioengineering; Cerebral Cortex; Drug Resistant Epilepsy; Epilepsy; Interictal activity; Largescale; Spikes; Microscale; SEEG; Models, Neurological; Brain; Computational modeling; Electroencephalography; Fast ripples; Spike-waves; Mesoscale; Humans; EEG

The aim is to gain insight into the pathophysiological mechanisms underlying interictal epileptiform discharges observed in electroencephalographic (EEG) and stereo-EEG (SEEG, depth electrodes) recordings performed during pre-surgical evaluation of patients with drug-resistant epilepsy.