COVID-19 in 96 Patients With Hematologic Disease: The First Single-center Experience From the Czech Republic

• DOI: 10.1016/j.clml.2021.04.016
• Publication Date: 2021-05-31T12:03:37Z
• Authors: Martin Čerňan; Tomáš Szotkowski; Aleš Obr; Vojtěch Látal; Antonín Hluší; Petra Krhovská; Olga Klementová; Milan Kolář; Pavel Sauer; Edgar Faber; Tomáš Fürst; Tomáš Papajík
• Keywords: Center (category theory); 2019-20 coronavirus outbreak; Single Center

Coronavirus disease 2019 (COVID-19) represents an important infectious complication associated with high mortality rates in patients hematologic diseases. There have not been published any epidemiologic studies from Czech Republic so far.This study is the first analysis of malignancies and bone marrow failure syndromes treated at single hematology center between March 1 December 31, 2020, whom COVID-19 infection was confirmed.The sample comprised 96 aged 26 to 84 years (median, 66.0 years). At time their diagnosis, 75 (78.1%) were for Twenty-seven (28.1%) had complete remission (CR) disease. They nonsignificantly more likely asymptomatic moderate than those who failed achieve CR (74.1% vs. 56.5%; P = .06). A severe course significantly correlated older age (P .047). Lung involvement also statistically .045). Over period, a total 15 died. Age greater 60 deaths .036), having nonsignificant impact on .22).These results confirm prognostic significance achieving treatment response as well severity patients.