Limb fat-free mass and fat mass reference values by dual-energy X-ray absorptiometry (DEXA) in a 20–80 year-old italian population

• DOI: 10.1016/j.clnu.2012.01.012
• Publication Date: 2012-02-16T13:01:37Z
• Authors: Alessandra Coin; Sandro Giannini; Nadia Minicuci; Giulia Rinaldi; Mario Pedrazzoni; Salvatore Minisola; Maurizio Rossini; Antonio Del Puente; Eminé Meral Inelmen; Enzo Manzato; Giuseppe Sergi
• Keywords: Adult; Male; Aging; DEXA; European Continental Ancestry Group; White People; fat-free mass; fat mass; DEXA; Young Adult; 03 medical and health sciences; Absorptiometry, Photon; 0302 clinical medicine; Retrospective Studie; Reference Values; 616; 80 and over; 617; Humans; Reference Value; Absorptiometry; Muscle, Skeletal; Aged; Retrospective Studies; Aged, 80 and over; Leg; dexa; fat mass; fat-free mass; limb composition; reference range; Fat mass; Body Weight; Limb composition; Skeletal; Reference range; Middle Aged; Photon; Fat-free mass; nutrition; Adipose Tissue; Italy; Body Composition; Muscle; Female; Human

To establish reference values for limb composition, fat-free mass (FFM) and fat mass (FM) in Italian adults for gender-specific age brackets 20-80 years old and to assess age-related regional changes in body composition.A multicenter, retrospective study was conducted on 1571 healthy subjects, 1240 women and 331 men. Regional FFM and FM were measured by dual-energy X-ray absorptiometry. FM was expressed as % of limb weight.FFM in men diminished with age in both arms and legs, with reference ranges (25th -75th percentile) of 3.8-4.6 kg and 10.4-12.2 kg, respectively for 20-29 year-olds, and 3.1-3.9 kg and 8.2-10.4 kg for 70-79 year-olds. Women's arm FFM remained stable with aging (reference values 1.7-2.2 kg), decreasing in their legs (6.2-7.2 kg for 20-29 year-olds, 5.5-6.5 kg for 70-79 year-olds). Limb FM% increased with age in both genders: the reference values were 9-15% (arms) and 12-21% (legs) for 20-29 year-old men, and 19-26% and 19-29%, respectively, for 70-79 year-olds; for women's arms, they were 25-36% for 20-29 year-olds and 36-48% for 70-79 year-olds, while their leg FM remained the same with aging, i.e. 32-40%.These data complete the published reference values for whole body composition, enabling physiological or pathological changes in limb composition to be identified in Caucasian populations living in the Mediterranean area.