Size Does Matter: Litter Size Strongly Determines Adult Metabolism in Rodents

• DOI: 10.1016/j.cmet.2020.07.014
• Publication Date: 2020-08-18T15:04:10Z
• Authors: Marcela Parra-Vargas; Marta Ramon-Krauel; Carles Lerin; Josep C. Jimenez-...
• Keywords: Litter

In this essay, we highlight how litter size in rodents is a strong determinant of neonatal growth and long-term metabolic health. Based on these effects, we strongly advise that scientific articles that utilize rodent models for obesity and metabolic research should include information on the litter sizes in the study to increase the data transparency of such reports.