Madurella mycetoma: a neglected tropical disease

• DOI: 10.1016/j.cmi.2021.04.018
• Publication Date: 2021-04-26T05:54:04Z
• Authors: Poornima Baby; Vipin Mohan; Malini Eapen; Anna Kurian; Arya Ramachandran; Balu C. Babu; Anil Kumar
• Keywords: Mycetoma; Foot (prosody); Tropical disease

Abstract Eumycotic mycetoma or eumycetoma is a chronic cutaneous and subcutaneous granulomatous infection caused by various fungi. A 65 year old gentleman presented with a history of nodular swellings on the right foot with discharging sinuses of six years duration. Radiological features showed signs of osteomyelitis. Histopathological examination of the tissue was suggestive of eumycetoma. Fungal culture of the granular discharge grew Madurella species. The patient responded well to itraconazole oral therapy, 200 mg twice daily. Eumycetoma relapses often occur, if surgical management with antifungal cover is not established at the earliest.