Strategies applied to modify structured and smooth surfaces: A step closer to reduce bacterial adhesion and biofilm formation

• DOI: 10.1016/j.colcom.2021.100560
• Publication Date: 2021-12-06T03:49:34Z
• Authors: A. Uneputty; A. Dávila-Lezama; D. Garibo; A. Oknianska; N. Bogdanchikova; J.F. Hernández-Sá...; A. Susarrey-Arce
• Keywords: Biocide; Bacterial growth

Nearly a century has passed since the discovery of first antibiotics. With each passing decade, more bacterial strains developed resistance towards existing Alternative methods to reduce contamination by bacteria and biofilms have arisen pressure on or currently This review highlights promising approaches prevent surface. Special attention is paid antibiotic-free antibacterial strategies that are not affected resistance. The been divided into four categories: (i) anti-adhesive, (ii) contact active, (iii) biocide attached/biocide release, which can be integrated with (iv) topographical modification. Anti-adhesive adhesion between solid surface from contacting contaminating Contact active provide activity attachment agents substratum. Biocide release integrates contact-release toxic chemicals attached Lastly, modification relies produce small structural features capable matching cellular components killing bacteria. Combining one lead robust approach deal dangerous pathogenic species. In this case, way forward combining various coatings onto topographically modified surfaces, enabling multifunctionality biofilm formation. A perspective current challenge provided.