Characteristics and co-morbidities associated with hospital discharges for opioid and methamphetamine co-use, United States 2016–2019

• DOI: 10.1016/j.dadr.2024.100219
• Publication Date: 2024-02-04T02:00:57Z
• Authors: Riley D. Shearer; Nathan D. Shippee; Beth A. Virnig; Timothy J. Beebe; Tyler N.A. Winkelman
• Keywords: CO poisoning; Methamphetamine; Co-occurrence

The US overdose crisis is increasingly characterized by opioid and methamphetamine co-use. Hospitalization an important opportunity to engage patients in substance use treatment. Understanding characteristics of co-use-related hospital stays can inform the development services better support this growing patient population. We used 2016–2019 National Inpatient Sample data conduct a cross sectional analysis hospitalizations involving opioids, methamphetamine, or both. bivariate compare demographics. then multinomial logistic regressions proportion which indicated co-morbid diagnosis. To account for correlated data, we generalized linear models outcomes mortality, patient-directed discharge, length stay. Co-use-related had higher mental health (60.7%; 95% CI: 59.9–61.4%) infectious diseases (41.5%; 40.8–42.2%), than opioid- methamphetamine-related stays. increased between 2016 2019 were associated with directed discharge (10.7%; 10.4–11.0%) longer stay (6.3 days; 6.2–6.4 days) compared (8.1%; 7.9–8.3% 5.8 5.8–5.9 (6.5%; 6.3–6.6% 5.5 5.4–5.5 days). Patients discharged co-use differ from alone, representing range challenges opportunities. In addition offering treatment both disorders, hospital-based that address co-occurring conditions may through targeted tailored approaches.