Molecular Basis of Natural Variation in Photoperiodic Flowering Responses
570
cis-regulatory changes
Photoperiod
Arabidopsis
Genetically Modified
Flowers
photoperiod
Databases
03 medical and health sciences
FT
florigen
Genetic
Gene Expression Regulation, Plant
Databases, Genetic
natural variation
transcription factor
0303 health sciences
Arabidopsis Proteins
500
flowering time
Plant
Plants
Plants, Genetically Modified
gibberellin
DNA-Binding Proteins
MYC3
Gene Expression Regulation
Trans-Activators
Signal Transduction
Transcription Factors
DOI:
10.1016/j.devcel.2019.05.018
Publication Date:
2019-06-06T14:34:24Z
AUTHORS (7)
ABSTRACT
Plants exhibit different flowering behaviors in response to variable photoperiods across a wide geographical range. Here, we identify MYC3, a bHLH transcription factor, and its cis-element form the long-sought regulatory module responsible for cis-regulatory changes at the florigen gene FLOWERING LOCUS T (FT) that mediate natural variation in photoperiodic flowering responses in Arabidopsis. MYC3 is stabilized by DELLAs in the gibberellin pathway to suppress FT through binding the ACGGAT motif and antagonizing CONSTANS (CO) activation. Changing photoperiods modulate the relative abundance of MYC3 and CO, thus determining either of them as the predominant regulator for FT expression under different day lengths. Cis-regulatory changes in the MYC3 binding site at FT are associated with natural variation in day-length requirement for flowering in Arabidopsis accessions. Our findings reveal that environmental and developmental signals converge at MYC3 suppression of FT, an elementary event underlying natural variation in photoperiodic flowering responses.
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