Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line

0301 basic medicine Q1-390 03 medical and health sciences Science (General) Computer applications to medicine. Medical informatics R858-859.7 Neuroscience
DOI: 10.1016/j.dib.2017.10.033 Publication Date: 2017-10-17T15:02:10Z
ABSTRACT
This set of experiments characterizes a model of transient cerebral ischemic stroke in a transgenic (Tg) mouse line in which the glial fibrillary acidic protein (GFAP) promoter is utilized to drive expression of a human RNA-binding protein, HuR. Additionally, the effect of cerebral ischemia on the expression of endogenous Hu proteins is presented.
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