Targeting NAT10 attenuates homologous recombination via destabilizing DNA:RNA hybrids and overcomes PARP inhibitor resistance in cancers

• DOI: 10.1016/j.drup.2025.101241
• Publication Date: 2025-03-23T05:46:26Z
• Authors: Zhu Xu; Mingming Zhu; Longpo Geng; Jun Zhang; Jing Xia; Qiang Wang; Hongda An; Anliang Xia; Yuanyuan Yu; Shihan Liu; Junjie Tong; Wei-Guo Zhu; Yiyang Jiang; Beicheng Sun
• Keywords: PARP inhibitor; Non-homologous end joining