Assessment of veterinary antibiotics from animal manure-amended soil to growing alfalfa, alfalfa silage, and milk

Silage Fodder Medicago sativa
DOI: 10.1016/j.ecoenv.2021.112699 Publication Date: 2021-08-25T23:23:29Z
ABSTRACT
Using animal manure as organic fertilizer to grow fodder crops is causing public health concerns because the major reservoir of veterinary antibiotics. In this study, we used a mathematical model estimate risk human exposure antibiotics when using swine alfalfa (Medicago sativa L.). Alfalfa was planted in greenhouse and fertilized with spiked oxytetracycline (OTC, at 0, 150, 1500 mg/kg manure), ofloxacin (OFL, 15, 150 mg/kg), or sulfamonomethoxine (SMM, 5, 15 mg/kg). harvested budding stage ensiled for 60 days. Results showed that OTC OFL could be detected root, stem, leaf concentration ranging from 8.85 59.17 μg /kg 1.50 4.10 OFL/kg dry matter, but SMM only root 29.10 63.75 μg/kg matter. The ensiling days decreased by 68.7% slightly concentration. maximum daily exposures humans through liquid milk consumption were estimated 5.84E-8 1.63E-8 μg, respectively, both which are well below intake levels (72 μg) (54 mandated European Union. results present study indicate poses limited milk.
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