Synthesis of chromone carboxamide derivatives with antioxidative and calpain inhibitory properties

• DOI: 10.1016/j.ejmech.2011.02.025
• Publication Date: 2011-02-23T09:52:26Z
• Authors: Sang Hoon Kim; Young Hoon Lee; Seo Yun Jung; Hyoung Ja Kim; Changbae Jin; Yong Sup Lee
• Keywords: Structure-Activity Relationship; 0303 health sciences; 03 medical and health sciences; Molecular Structure; Calpain; Chromones; Stereoisomerism; Lipid Peroxidation; Antioxidants; 3. Good health

AbstractNew chromone carboxamide derivatives like (I) are synthesized by conventional procedures to provide alternative μ‐calpain inhibitors to other conformationally constrained small peptide variants.