Discovery of novel dihydropteridone derivatives as orally bioavailable PLK1 inhibitors with reduced hERG inhibitory activity for acute myeloid leukemia treatment

• DOI: 10.1016/j.ejmech.2025.117480
• Publication Date: 2025-03-07T07:53:00Z
• Authors: Yunlei Hou; Shuang Li; Le Ren; Long Zhang; Na Zhang; Ruifeng Miao; Qi Huang; Zhiwei Li; Changliang Hu; Zhiguo Xi; Minghui Tong; Ping Gong; Yanfang Zhao; Yajing Liu; Jiuyu Liu