Risk factors for ectopic pregnancy in women with planned pregnancy: a case–control study

• DOI: 10.1016/j.ejogrb.2014.07.049
• Publication Date: 2014-08-08T00:02:03Z
• Authors: Cheng Li; Chun-Xia Meng; Wei-Hong Zhao; Hai-Qian Lu; Wei Shi; Jian Zhang
• Keywords: Pelvic inflammatory disease; Tubal factor infertility

<h2>Abstract</h2><h3>Objective</h3> To explore the risk factors for ectopic pregnancy (EP) in women with planned pregnancy. <h3>Study design</h3> This case–control study was conducted and included 900 diagnosed EP (case group) 889 intrauterine (IUP) as control group matched terms of age gestational week. Socio-demographic characteristics, reproductive history, gynecological surgical previous contraceptive use, history infertility were compared between two groups. Blood samples collected from all participants to detect serum chlamydia trachomatis (CT) IgG antibody. The odds ratio (OR) its 95% confidential interval (CI) each variable calculated by univariable conditional logistic regression analysis. Factors significantly different both groups, revealed analysis, entered into a multivariable model stepwise selection. <h3>Results</h3> associated adnexal surgery (adjusted OR=3.99, CI: 2.40–6.63), uncertainty pelvic inflammatory disease OR=6.89, 3.29–14.41), positive CT serology OR=5.26, 3.94–7.04). A including tubal OR=3.62, 1.52–8.63), non-tubal OR=3.34, 1.60–6.93), <i>in vitro</i> fertilization (IVF) treatment OR=5.96, 1.68–21.21) correlated EP. Women who had previously used condoms less likely have during current cycle OR=0.27, 0.21–0.36). <h3>Conclusions</h3> Besides well-acknowledged EP, attention should be paid and/or IVF treatment, prevent complications