Deprived neighborhoods and spontaneous preterm birth: A national cohort study

• DOI: 10.1016/j.ejogrb.2022.05.012
• Publication Date: 2022-05-20T02:41:11Z
• Authors: Job Klumper; Anita C.J. Ravelli; Carolien Roos; Ameen Abu-Hanna; Martijn A. Oudijk
• Keywords: Social Deprivation; Singleton; Odds; Premature birth; Parity (physics)

Spontaneous preterm birth is the leading cause of infant morbidity and mortality in developed world. Environmental socio-economic factors, such as neighborhood deprivation, are known to negatively affect outcomes, including overall birth. However, role deprivation spontaneous (SPTB) unclear. The aim study 1) determine effect on SPTB 2) investigate trend rates between 2010 2019 for each quintile deprivation.Based national perinatal registry, we included 1,584,225 singleton pregnancies resulting a from 22 42 completed weeks gestation Netherlands. Deprivation scores per were derived Netherlands Institute Social Research linked registry data, using woman's home address. divided into quintiles (Q). Rates calculated, categorized <37 weeks, <32 <28 gestation. We used logistic regression analysis adjust maternal age, parity ethnicity.Compared most affluent neighborhoods (Q1), women all other had statistically significant increased risk SPTB. largest was observed deprived (Q5); adjusted odds ratio 1.16 (95% confidence interval 1.13 - 1.19). From 2019, an decrease 0.21% < 37 (p 0.0001). All showed SPTBs but only Q1, Q2 & Q5 this decline significant.Pregnant more at rate decreased. Efforts should be made by both governmental medical professionals develop intervention programs reduce neighborhoods.