Diffusion weighted MRI and transient elastography assessment of liver fibrosis in hepatitis C patients: Validity of non invasive imaging techniques

• DOI: 10.1016/j.ejrnm.2014.02.007
• Publication Date: 2014-05-14T21:53:58Z
• Authors: Fatma Zaiton; Hitham Dawoud; Inas M. El Fiki; Khaled M. Hadhoud
• Keywords: Transient elastography; Histopathology; Hepatic fibrosis; Hepatitis C

Treatment for hepatitis C infection and monitoring of progression were based on degree fibrosis, which traditionally diagnosed by liver biopsy but it has many limitations. We aim to evaluate noninvasive imaging methods, so-called diffusion-weighted MRI (DW MRI) transient elastography [(TE), fibroscan] in diagnosing fibrosis (HCV) patients. The Study included 102 patients (62 male) with mean age 38 ± 5. For all was done followed DW TE. METAVIR classification system used staging fibrosis. Data obtained collected results TE compared those histopathology. diagnostic performance ADC determined using areas under receiver operating characteristic (AUROC) curves significant ⩾F3. Measuring at different b-values had a negative correlation stage P = 0.001, the best b-value 700 mm2/s. positive 0.005. Both examination showed difference between <F3 stages ⩾F3 < 0.00 measure each respectively. This study suggests that favorable comparable diagnosis