Cardiac Outcomes in Isolated Heart and Simultaneous Kidney and Heart Transplants in the United States

• DOI: 10.1016/j.ekir.2021.06.032
• Publication Date: 2021-07-14T17:04:07Z
• Authors: Krishna Adit Agarwal; Het Patel; Nikhil Agrawal; Francesca Cardarelli; Nitender Goyal
• Keywords: Renal replacement therapy; Heart transplants

Kidney dysfunction is not uncommon in patients with advanced heart failure. Simultaneous kidney and transplants (SKHTs) have gained acceptance as a treatment for end-stage failure severe dysfunction. United States saw rise of 650% SKHT from 2000 to 2019. Despite increasing number SKHT, the selection criteria remain poorly defined vary across transplant centers.We evaluated patient cardiac allograft survival alone (HTA) using Network Organ Sharing (UNOS) database. We then performed subgroup analysis recipients post-transplant acute injury requiring renal replacement therapy (RRT) compared outcomes between HTA recipients.Although was comparable groups (12.4 vs. 11.3 years), dependent on dialysis pretransplant derived greater advantage 9.9 years). Cardiac graft better (12.5 11.2 Among who developed RRT postoperatively, had significantly (11.9 2.7 years).Our data support consideration dialysis-dependent candidates suggest that are at increased risk after may benefit SKHT.