Using alteplase nephrostomy tube installation for thrombolysis of ureter tract clot obstruction

• DOI: 10.1016/j.eucr.2021.101561
• Publication Date: 2021-01-14T06:27:27Z
• Authors: Paoyan Lin; Tomasz Fiutowski; Christoph Ansorge
• Keywords: Thrombolytic therapy; Tissue plasminogen activator; Nephrostomy; 03 medical and health sciences; 0302 clinical medicine; Ureteral obstruction; RC870-923; Endourology; Diseases of the genitourinary system. Urology; Percutaneous; 3. Good health

In literature, few cases have been reported regarding the use of alteplase installation in a nephrostomy as anticoagulant treatment of blood clots in the upper urinary tract. Our case -report provides a unique case of alteplase installation in the nephrostomy tube for thrombolysis of a blood clot formation in the upper ureter. The blood clot formation emerged as acute obstruction following a planned endoscopic lithotripsy. A new protocol for alteplase installation for percutaneous nephrostomy is presented in this article.