Trait anxiety is associated with attentional brain networks

• DOI: 10.1016/j.euroneuro.2024.02.013
• Publication Date: 2024-03-16T01:30:16Z
• Authors: Víctor De la Peña...; Pamela Chavarría-...; Asier Juaneda-Seguí; Ignacio Martínez-...; Pedro Morgado; José Manuel Menchón; Maria Picó-Pérez; Miquel A. Fullana; Carles Soriano-Mas
• Keywords: Trait; Trait anxiety

Trait anxiety is a well-established risk factor for and depressive disorders, yet its neural correlates are not clearly understood. In this study, we investigated the of trait in large sample (n = 179) individuals who completed state versions State-Trait Anxiety Inventory underwent resting-state functional magnetic resonance imaging. We used independent component analysis to characterize individual networks (RSNs), multiple regression analyses assess relationship between intrinsic connectivity. was significantly associated with connectivity different regions three RSNs (dorsal attention network, default mode auditory network) when controlling anxiety. These primarily support attentional processes. Notably, controlled for, pattern results emerged, highlighting importance considering assessing Our findings suggest that uniquely brain mainly supporting Moreover, crucial insights may help refine current neurobiological models identify potential targets neurobiologically-based interventions.