Synthesis of silver nanoparticles from red and green parts of the pistachio hulls and their various in-vitro biological activities

• DOI: 10.1016/j.fct.2022.113170
• Publication Date: 2022-05-22T05:20:15Z
• Authors: Serpil Gonca; Sadin Özidemir; Zelal Isik; Islem M'barek; Feroz Shaik; Nadir Dizge; Deepanraj Balakri...
• Keywords: 0303 health sciences; 03 medical and health sciences; Silver; Plant Extracts; Pistacia; Escherichia coli; Metal Nanoparticles; Microbial Sensitivity Tests; Anti-Bacterial Agents

In this study, synthesis of silver nanoparticles (AgNPs) was carried out utilizing the red and green parts of the pistachio hulls then their several biological activities were investigated. The DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) activities of the AgNPs synthesized from red pistachio hulls extracts (PhR-AgNPs) and green pistachio hulls extracts (PhG-AgNPs) were investigated. The DPPH scavenging capability at 200 mg/L concentration of PhR-AgNPs was around 93.01% however PhG-AgNPs displayed 91.00%. The synthesized PhR-AgNPs and PhG-AgNPs acted on the E. coli plasmid DNA, causing its complete degradation and exhibiting effective chemical nuclease activity. Furthermore, PhR-AgNPs and PhG-AgNPs showed quite good antimicrobial activity against the studied strains with a range of the minimum inhibition concentration (MIC) of 8-16 mg/L. Moreover, it was observed that both pistachio hulls coated with AgNPs were highly effective in inhibiting the biofilm generation studied strains. Moreover, PhR-AgNP and PhG-AgNP displayed a completely inhibition effect on cellular viability of E. coli with 100% at 125 mg/L.