Biological factors controlling starch digestibility in human digestive system

• DOI: 10.1016/j.fshw.2022.07.037
• Publication Date: 2022-09-07T17:02:55Z
• Authors: Cheng Li; Yiming Hu; Songnan Li; Xueer Yi; Shuaibo Shao; Wenwen Yu; Enpeng Li
• Keywords: Digestion; Intestinal motility; Human gastrointestinal tract; Digestive tract; Resistant Starch

Starch digestion rate and location in the gastrointestinal tract (GIT) are critical for human health. This review aims to present a comprehensive summary on our current understanding of physiological, biochemical, anatomical geometrical factors digestive system that related vivo starch digestibility. It is shown all compartments including mouth, stomach, small intestine, large intestine play roles regulating overall process. A proper investigation pattern should thus be based consideration these compartments. Main biological summarized as oral mastication salivation, gastric emptying motility, intestinal enzymes resistant (RS)-microbiota interactions gut-brain feedback control, well glucose adsorption hormonal control. However, connections among determining behaviors remain elusive. due inherent complexity GIT anatomy, motility biochemical conditions, ethical, financial technical issues conducting clinical studies. Much technological scientific efforts from both studies vitro simulation models required better behaviors.