InfiniumPurify: An R package for estimating and accounting for tumor purity in cancer methylation research

• DOI: 10.1016/j.gendis.2018.02.003
• Publication Date: 2018-02-21T10:11:29Z
• Authors: Yufang Qin; Hao Feng; Ming Chen; Hao Wu; Xiaoqi Zheng
• Keywords: Sample (material)

The proposition of cancer cells in a tumor sample, named as purity, is an intrinsic factor samples and has potentially great influence variety analyses including differential methylation, subclonal deconvolution subtype clustering. InfiniumPurify integrated R package for estimating accounting purity based on DNA methylation Infinium 450 k array data. three main functions getPurity, InfiniumDMC InfiniumClust, which could infer analysis sample cluster estimated or user-provided purities, respectively. provides comprehensive research.