How much are metals for next-generation clean technologies harmful to aquatic animal health? A study with cobalt and nickel effects in zebrafish (Danio rerio)

• DOI: 10.1016/j.hazadv.2022.100160
• Publication Date: 2022-09-05T07:32:57Z
• Authors: Andreia Cristina ...; Patrícia Thieme O...; Rafaella da Silva...; Paulo Sérgio Scalize; Thiago Lopes Rocha
• Keywords: Danio; Cardiotoxicity; Developmental toxicity; Aquatic toxicology

Cobalt (Co) and nickel (Ni) are key metals for next-generation clean technologies with broad applications in industrial, military commercial products. However, the knowledge about their environmental impact toxicity to aquatic organisms remain limited, especially early developmental stages of fish. Thus, current study aimed evaluate Co Ni zebrafish (Danio rerio). Zebrafish embryo-larval test (ZELT) was conducted at different concentrations (10, 20, 40, 60, 80 100 mg L−1) during 144 h a static condition. Multiple biomarker responses were analyzed, such as mortality, hatching rate, neurotoxicity, cardiotoxicity, teratogenesis, morphometric changes. Results showed high embryotoxicity compared Co. Both inhibited process induced morphological changes, inhibition swim bladder inflation, yolk sac edema pericardial edema. bradycardia embryos, while caused tachycardia, indicating differential cardiotoxic effects. Overall, exposure disrupts development zebrafish, confirming risk health freshwater indicated ZELT suitable approach assess technologies.