Guillain-Barré syndrome following the first dose of SARS-CoV-2 vaccine: A temporal occurrence, not a causal association

• DOI: 10.1016/j.idcr.2021.e01143
• Publication Date: 2021-04-30T17:08:51Z
• Authors: Osakpolor Ogbebor; Harshit Seth; Zaw Min; Nitin Bhanot
• Keywords: Pandemic; Causality; Vaccine safety; 2019-20 coronavirus outbreak

Safety monitoring is of paramount importance for vaccines authorized emergent use (EUA) by the US Food and Drug Administration (FDA) against SARS-CoV-2. Mass immunization an essential tool to end current pandemic, but vaccine surveillance necessary identify any potentially associated harms. At same time, probability temporal bias should be borne in mind before making conclusions about causality between attributable undesired effect. We report a case Guillain-Barré syndrome after first dose SARS-CoV-2 believe this temporal, rather than causal association.