Immune thrombocytopenia relapse post covid-19 vaccine in young male patient

• DOI: 10.1016/j.idcr.2021.e01344
• Publication Date: 2021-11-17T10:58:58Z
• Authors: Hana Qasim; Elrazi Ali; Mohamad A. Yassin
• Keywords: Thrombocytopenic purpura; Pathophysiology

Immune thrombocytopenic purpura (ITP) is a blood disorder in which antibodies coating platelets cause destruction the spleen with resultant low count and an increased tendency for bleeding. Coronavirus disease 2019 (COVID-19) illness caused by SARS-COV2; it was first identified December/2019; though mainly affects respiratory system, multisystemic complications are identified. Several ITP cases post mRNA SARS-CoV-2 vaccines were reported, different pathophysiology theories about underlying discussed, but only few relapse have been reported so far. We present 28-year-old Asian male, known patient of partial remission eighteen months, who presented to emergency department (platelets 1 × 10^3 /µL), four days after receiving second dose Pfizer vaccine, required treatment intravenous immunoglobulins dexamethasone. further discuss preferred approach patients willing receive COVID-19 vaccine.