Mechanical circulatory device utilization in cardiac arrest: Racial and gender disparities and impact on mortality

• DOI: 10.1016/j.ijcard.2022.09.004
• Publication Date: 2022-09-07T15:28:12Z
• Authors: Aamir Gilani; Arish Maknojia; Muhammad Mufty; Shaan Patel; Cindy L. Grines; Abhijit Ghatak
• Keywords: Male; Adult; Intra-Aortic Balloon Pumping; Shock, Cardiogenic; Heart Arrest; 3. Good health; 03 medical and health sciences; Extracorporeal Membrane Oxygenation; Treatment Outcome; 0302 clinical medicine; Humans; Female; Heart-Assist Devices; Retrospective Studies

The objectives of this retrospective study include identifying the utilization trend of mechanical circulatory devices (MCD) such as Intra-Aortic Balloon Pump (IABP), Impella and Extracorporeal Membrane Oxygenation (ECMO) in admissions with cardiac arrest, determining whether racial or gender disparities exist in their usage, and discerning if their use is associated with a reduction in mortality. By leveraging the National Inpatient Sample, we identified 229,180 weighted adult cardiac arrest admissions between October 1, 2015 and December 31, 2018. MCD were used in 6005 admissions (2.6%). IABP had the highest utilization, representing 77.8% of all MCDs, followed by Impella at 24.8%. The utilization of IABP decreased from 90.6% to 71.6%, while the use of Impella increased from 13.5% to 29.8% in this study period; both trends were statistically significant. MCD use was found to be lower in women compared to men (1.4% vs 3.6, P < 0.001) and in the Black population compared to White (1.5% vs 2.8%, P < 0.001). There was no difference in MCD utilization between Hispanic and the White cohorts. In-hospital mortality was lower in admissions associated with MCD (31.4% vs 45.9%, P < 0.001). ECMO was associated with the lowest mortality rate at 14.3%, followed by IABP at 28.1%. The use of Impella and combination therapy were not associated with a significant decrease in mortality. In conclusion, MCD use may decrease mortality in cardiac arrest, however their utilization appears to be lower in African Americans and in women.