Non-tuberculous mycobacterial infections—A neglected and emerging problem

• DOI: 10.1016/j.ijid.2020.02.022
• Publication Date: 2020-02-27T16:39:36Z
• Authors: Imran Ahmed; Simon Tiberi; Joveria Farooqi; Kauser Jabeen; Dorothy Yeboah-Manu; Giovanni Battista...; Rumina Hasan
• Keywords: Isolation; Nontuberculous Mycobacteria

Non-tuberculous mycobacteria (NTM) are ubiquitous dwellers of environmental niches and an established cause natural nosocomial infections. The incidence NTM infections is rising owing to a growing population immunocompromised vulnerable individuals, complex medical surgical procedures, as well increased awareness diagnostic capabilities. prevalence different varies between continents, regions, countries. true global burden pulmonary extrapulmonary disease unknown estimates subject under and/or over-estimation. Diagnosis requires confirmation by isolation along with clinical radiological criteria, which may be suboptimal at all levels. Susceptibility testing breakpoints not available for many the drugs. Frequently, considered until late in course disease. Improved rapid detection tuberculosis cases high-burden countries has, however, also brought into limelight, has identified need research efforts towards tests identification biomarkers monitor treatment response patients