Epidemiology of concurrent extrapulmonary tuberculosis in inpatients with extrapulmonary tuberculosis lesions in China: a large-scale observational multi-centre investigation

• DOI: 10.1016/j.ijid.2021.11.019
• Publication Date: 2021-11-12T16:21:12Z
• Authors: Wanli Kang; Shengsheng Liu; Jian Du; Peijun Tang; Hongyan Chen; Jianxiong Liu; Jinshan Ma; Mingwu Li; Jingmin Qin; Wei Shu; Peilan Zong; Yi Zhang; Yongkang Dong; Zhiyi Yang; Zaoxian Mei; Qunyi Deng; Pu Wang; Wenge Han; Xiaofeng Yan; Ling Chen; Xinguo Zhao; Lei Tan; Fujian Li; Chao Zheng; Hongwei Liu; Xinjie Li; Ertai A; Yingrong Du; Fenglin Liu; Wenyu Cui; Quanhong Wang; Xiaohong Chen; Junfeng Han; Qingyao Xie; Yanmei Feng; Wenyu Liu; Song Yang; Jianyong Zhang; Jian Zheng; Dawei Chen; Xiangyang Yao; Tong Ren; Yan Li; Yuanyuan Li; Lei Wu; Qiang Song; Xinghua Shen; Jian Zhang; Yuanyuan Liu; Shuliang Guo; Kun Yan; Mei Yang; Dan Lei; Yanli Zhang; Meiying Wu; Liang Li; Shenjie Tang
• Keywords: Extrapulmonary tuberculosis

AimsA high proportion of all patients with tuberculosis (TB) present extrapulmonary TB (EPTB), including concurrent EPTB involving more than one lesion site. However, previous reports only characterized lesions single-site cases. This study aimed to investigate epidemiological characteristics and association rules cases in China.MethodsAn observational multi-centre 208,214 was undertaken China from January 2011 December 2017. Multi-variable logistic regression analysis used identify associations between gender EPTB, age EPTB. Association were analysed for significance using the Apriori algorithm.ResultsThe most common tuberculous pleurisy (49.8%), followed by bronchial (14.8%) meningitis (7.6%). The type peritonitis (1.80%). In total, 22 rules, 20 strong identified; among these, highest confidence rates found myelitis meningitis, sacral lumbar vertebral TB. other types vary age. rate higher females (83.67%) males, aged 25–34 years (87.50%).ConclusionsMany found. Greater awareness disease is needed ensure timely clinical diagnosis treatment this disease.