Neurocognitive deficits and sequelae following severe hand, foot, and mouth disease from 2009 to 2017, in JiangSu Province, China: a long-term follow-up study

• DOI: 10.1016/j.ijid.2021.11.026
• Publication Date: 2021-12-12T18:39:44Z
• Authors: Hong Ji; Huan Fan; Jing Ai; Chao Shi; Jun Bi; Yin-Hua Chen; Xiao-Peng Lu; Qin-Hui Chen; Jian-Mei Tian; Chang-jun Bao; Xue-feng Zhang; Yu Jin
• Keywords: Neurocognitive

The aim of this study was to evaluate the long-term sequelae and cognitive profiles resulting from severe hand, foot, mouth disease (HFMD) with central nervous system (CNS) involvement.294 HFMD cases were included in a retrospective follow-up study. Physical examinations conducted. Chinese Wechsler Preschool Primary Scale Intelligence, Fourth Edition (WPPSI-IV) used assess intelligence.58 mild 99 CNS involvement did not present any neurological sequelae. In comparison, incidence for more complications 50.0%. proportion full-scale intelligence quotient (FSIQ) impairment 45.0%. 2:6-3:11 age group, lower maternal education level risk factors verbal comprehension disorder. Urban-rural residence paternal FSIQ Furthermore, 4:0-6:11 complication factor visual spatial disorder fluid reasoning Lower disorder.Early assessment intervention among patients at very young will prove beneficial their future performance.