Oral management in a patient with Gardner-Diamond Syndrome: A case report

• DOI: 10.1016/j.ijscr.2020.09.098
• Publication Date: 2020-09-17T17:04:02Z
• Authors: Ambre Bellot; Rémi Curien; Anaïs Derache; Bruno Delaître; Raffaele Longo; Yinka Zevering; Julie Guillet; Bérengère Phulpin
• Keywords: [SDV] Life Sciences [q-bio]; 03 medical and health sciences; 0302 clinical medicine; [SDV]Life Sciences [q-bio]; Case Report; 3. Good health

Gardner-Diamond Syndrome (GDS) is rare. It characterized by the spontaneous formation of painful erythematous skin lesions that develop into ecchymoses within 24 h and then disappear progressively over days to weeks. The complications can be serious. A 35-year-old man with GDS was admitted oral surgery department for dental infectious focus eradication. Clinical radiological examinations indicated extraction tooth 17. performed local anaesthesia, cardiac monitoring, verbal reassurance therapy. After delivering two intra-oral hematomas a bruise quickly developed. Cardiovascular manifestations right temporal lesion appeared in next h. patient briefly hospitalized cardiovascular medicine department. Over 21 days, some haematomas regressed, another expanded, new cervico-thoracic ecchymosis surgical post-surgical this clinical case raise several points concerning management patients GDS. We propose apply: therapy during surgery; presurgical haematological evaluation postsurgical daily follow-up; atraumatic intra- haemostatic precautions. Systematic antibiotic prophylaxis non-steroidal anti-inflammatory drugs may also useful. Other possibilities include desmopressin acetate, corticosteroids, antihistamines, plasmapheresis, immunosuppressive agents; however, few cases have been treated these strategies. This highlights difficult who require surgery. Further studies are needed improve procedures establish systematic algorithm.