Effect of herbal medicine (Jodeungsan) on migraine: A double-blind randomized clinical trial
03 medical and health sciences
0302 clinical medicine
Jodeungsan
RZ409.7-999
Headache attack days
Original Article
Herbal medicine
Miscellaneous systems and treatments
Migraine
Placebo
3. Good health
DOI:
10.1016/j.imr.2022.100885
Publication Date:
2022-08-05T16:44:07Z
AUTHORS (9)
ABSTRACT
Migraine is a relatively common disease that has a significant effect on the daily activities of affected individuals. The purpose of this study was to explore the effects of herbal medicine (Jodeungsan, JDS) on migraine.Sixty-four patients with migraine were recruited and randomized to either the JDS or placebo group at a 1:1 ratio. The subjects received JDS or placebo daily for four weeks. The primary outcome was a change in the number of headache attack days (HADs), and the secondary outcome measures were the headache impact test (HIT), migraine-specific quality of life (MSQoL), the deficiency and excess pattern identification questionnaire (DEPIQ), the cold and heat pattern identification questionnaire (CHPIQ), and the blood stasis pattern questionnaire (BSPQ).In all, 61 of the 64 patients took the investigational drugs for four weeks. The number of HADs did not significantly differ between the JDS and placebo groups at the end of the study. However, the HIT and MSQoL results showed significant improvement over the baseline in both groups.JDS did not have a significant effect on chronic migraine. Larger studies are needed to confirm this result.Clinical Research Information Service (https://cris.nih.go.kr/): KCT0003121.
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