Okra seed polysaccharides mitigate neuroinflammation and cognitive impairment via modulation of Nrf2/HO-1, HMGB1/RAGE/TLR4/NF-κB, NLRP3/Caspase-1, JAK-2/STAT-3, AMPK/SIRT1/m-TOR, PI3K/AKT/CREB/BDNF/TrkB and PERK/CHOP/Bcl-2 axes

• DOI: 10.1016/j.intimp.2025.114110
• Publication Date: 2025-01-24T10:21:32Z
• Authors: Jilan A. Nazeam; Ian Black; Varughese A. Mula...; Nabil M. Selim; Riham A. El Shiekh; Karema Abu-Elfotuh; Ahmed M.E. Hamdan; Ayah M.H. Gowifel; Shaimaa M. Hafez; Ehsan K. Mohamed; Ahmed M. Atwa; Hala Mohamed El H...; Parastoo Azadi
• Keywords: HMGB1; RAGE