Randomized controlled trial examining the adjunctive use of nicotine lozenges with MyLastDip: An eHealth smokeless tobacco cessation intervention

• DOI: 10.1016/j.invent.2014.12.004
• Publication Date: 2014-12-23T04:46:40Z
• Authors: Brian G. Danaher; Herbert H. Severson; Ryann Crowley; Nora van Meter; Milagra S. Tyler; Chris Widdop; Edward Lichtenstein; Jon O. Ebbert
• Keywords: Lozenge; Nicotine replacement therapy; Clinical endpoint; eHealth

Promising Web-based interventions for smokeless tobacco cessation have emerged. We describe a randomized controlled trial (RCT) testing the relative benefits of adding nicotine lozenge as an adjunct to MyLastDip intervention. 407 users who wanted quit were recruited, screened online, and randomly assigned one two conditions: (a) interactive intervention (Web Only; n = 202), or (b) website plus offer lozenges + Lozenge; 205). program content is grouped according three sequential frames: preparing quit, quitting, staying quit. If participant reported lapse then would provide tailored on lessons learned starting over ("retooling"). The primary outcome was 7-day point prevalence abstinence measured at follow-up assessments that occurred 3 months 6 post-enrollment. Assessment completion rates 71.5% months, 72.9% 65.1% both did not differ by condition. Using Intent Treat analyses, Web Lozenge condition associated with significantly higher rate than Only (43.4% vs. 29.7%, p .004), combined month assessment repeated (35.6% 23.3%, .007), but (44.4% 35.1%, .057). Similar results obtained abstinence. Participants being satisfied their programs participants visited more often (p < .001). A composite engagement measure number duration visits positively related 6-month .009). Consistent previous research, encouraged long-term levels addition improved self-reported when considering 3-