Real-time monitoring of deformed wing virus-infected bee foraging behavior following histone deacetylase inhibitor treatment

• DOI: 10.1016/j.isci.2021.103056
• Publication Date: 2021-09-28T16:00:42Z
• Authors: Cheng-Kang Tang; Yu-Hsien Lin; Joe-Air Jiang; Yun-Heng Lu; Chih-Hsuan Tsai; Yu-Chun Lin; Yun-Ru Chen; Carol-P Wu; Yueh-Lung Wu
• Keywords: Deformed wing virus; Bumblebee

Impairment in the learning/memory behavior of bees is responsible for massive disappearance bee populations and its consequent agricultural economic losses. Such impairment might be because o both pesticide exposure pathogen infection, with a key contributor deformed wing virus (DWV). The present study found that sodium butyrate (NaB) significantly increased survival reversed DWV-infected bees. A next-generation sequencing analysis showed NaB affected expression genes involved glycolytic processes memory formation, which were suppressed by DWV infection. In addition, we performed large-scale movement tracking experiment using wireless sensor network-based automatic real-time monitoring system confirmed could improve homing ability short, demonstrated mechanism how epigenetic regulation can resume function honeybees suggest strategies applying to reduce incidence colony