Dormant Nfatc1 reporter-marked basal stem/progenitor cells contribute to mammary lobuloalveoli formation

• DOI: 10.1016/j.isci.2022.103982
• Publication Date: 2022-02-26T08:08:17Z
• Authors: Ruiqi Liu; Huan Hu; Melissa McNeil; Jiuzhi Xu; Xueyun Bi; Pengbo Lou; Christian F. Guer...; Xing Dai; Maksim V. Plikus; Jianwei Shuai; Zhengquan Yu; Cong Lv
• Keywords: Basal (medicine)

The Mammary gland undergoes complicated epithelial remodeling to form lobuloalveoli during pregnancy, in which basal cells remarkably increase a basket-like architecture. However, it remains largely unknown how dormant mammary stem/progenitor involve lobuloalveolar development. Here, we show that