Association between cumulative lipoprotein(a) exposure and adverse cardiovascular outcomes in patients with prediabetes or diabetes

• DOI: 10.1016/j.isci.2023.106117
• Publication Date: 2023-02-02T20:07:13Z
• Authors: Peizhi Wang; Deshan Yuan; Ce Zhang; Sida Jia; Ying Song; Xiaofang Tang; Xueyan Zhao; Runlin Gao; Bo Xu; Jinqing Yuan
• Keywords: Prediabetes

Few studies have characterized long-term exposure to lipoprotein(a), or Lp(a), different glucose metabolism status, and their joint role in adverse cardiovascular outcomes risk. We consecutively enrolled 10,724 coronary heart disease (CAD) patients from January December 2013 Fuwai Hospital. Associations of cumulative lipoprotein(a) (CumLp(a)) status with major cardiac cerebrovascular events (MACCEs) risk were evaluated using Cox regression models. Compared participants normal regulation lower CumLp(