CRISPR/Cas9-mediated SHP-1-knockout T cells combined with simvastatin enhances anti-tumor activity in humanized-PDX HCC model

• DOI: 10.1016/j.isci.2025.112266
• Publication Date: 2025-03-22T23:11:16Z
• Authors: Huaping Liu; Wu Ge; Xiaoping Yu; Jianwei Luo; Juan Zhang; Min Yang; Lu Cao; Yangnan Zhang; Ruike Wang; Cejun Yang; Pei Li; Mengyu Tian; XiaoPei Peng; Lei Peng; Di Wu; Muqi Liu; Qi Liang; Shengwang Zhang; Wei Li; Pengfei Rong; Hailan Li; Xiaoqian Ma; Wei Wang