Quantification of stenotic mitral valve area with magnetic resonance imaging and comparison with Doppler ultrasound

• DOI: 10.1016/j.jacc.2004.03.038
• Publication Date: 2004-07-02T18:52:12Z
• Authors: Shiow Jiuan Lin; Peggy A. Brown; Mary P. Watkins; Todd A. Williams; Katherine A. Lehr; Wei Liu; Gregory M. Lanza; Samuel A. Wickline; Shelton D. Caruthers
• Keywords: Repeatability; Doppler ultrasound; Mitral valve stenosis; Cardiac magnetic resonance

The purpose of this study was to evaluate the reliability of the pressure half-time (PHT) method for estimating mitral valve areas (MVAs) by velocity-encoded cardiovascular magnetic resonance (VE-CMR) and to compare the method with paired Doppler ultrasound.The pressure half-time Doppler echocardiography method is a practical technique for clinical evaluation of mitral stenosis. As CMR continues evolving as a routine clinical tool, its use for estimating MVA requires thorough evaluation.Seventeen patients with mitral stenosis underwent echocardiography and CMR. Using VE-CMR, MVA was estimated by PHT method. Additionally, peak E and peak A velocities were defined. Interobserver repeatability of VE-CMR was evaluated.By Doppler, MVAs ranged from 0.87 to 4.49 cm2; by CMR, 0.91 to 2.70 cm2, correlating well between modalities (r = 0.86). The correlation coefficient for peak E and peak A between modalities was 0.81 and 0.89, respectively. Velocity-encoded CMR data analysis provided robust, repeatable estimates of peak E, peak A, and MVA (r = 0.99, 0.99, and 0.96, respectively).Velocity-encoded cardiovascular magnetic resonance can be used routinely as a robust tool to quantify MVA via mitral flow velocity analysis with PHT method.