Saliva contact during infancy and allergy development in school-age children

• DOI: 10.1016/j.jacig.2023.100108
• Publication Date: 2023-04-11T06:52:37Z
• Authors: Yoshimi Kubo; Nobuo Kanazawa; Hironobu Fukuda; Yutaka Inaba; Naoya Mikita; Masatoshi Jinnin; Fukumi Furukawa; Yasushi Kuraishi; Shigemi Yoshihara
• Keywords: Interquartile range; Pacifier

Parent-child saliva contact during infancy might stimulate the child's immune system for effective allergy prevention. However, few studies have investigated its relation to development in school-age children.We sought investigate relationship between parent-child and at school age.We performed a large multicenter cross-sectional study involving Japanese children their parents. The self-administered questionnaires including questions from International Study of Asthma Allergies Childhood were distributed 3570 elementary junior high 2 local cities. Data analyzed (age <12 months) risk development, specifically eczema, allergic rhinitis, asthma. For detailed Methods, please see Methods section this article's Online Repository www.jacionline.org.The valid response rate was 94.7%. mean median age 10.8 ± 2.7 11 (interquartile range, 9-13) years, respectively. Saliva via sharing eating utensils significantly associated with lower eczema (odds ratio, 0.53; 95% CI, 0.34-0.83) age. parental sucking pacifiers 0.24; 0.10-0.60) rhinitis 0.33; 0.15-0.73), had borderline association asthma children.Saliva may reduce developing children.