Percutaneous Left Atrial Appendage Closure With the LAmbre Device for Stroke Prevention in Atrial Fibrillation

• DOI: 10.1016/j.jcin.2017.06.072
• Publication Date: 2017-11-06T22:17:12Z
• Authors: He Huang; Yu Liu; Yawei Xu; Zulu Wang; Yigang Li; Kejiang Cao; Shu Zhang; Yanzong Yang; Xinchun Yang; Dejia Huang; Bo Yu; Xi Su; Liqun Wu; Congxin Huang
• Keywords: Stroke; Atrial Appendage; Appendage; Closure (psychology); Thromboembolic stroke

The authors sought to assess the clinical outcomes of left atrial appendage (LAA) closure with the LAmbre closure system in patients with nonvalvular atrial fibrillation (NVAF).Over 90% of thrombi are located in the LAA in NVAF patients.A prospective, multicenter study was conducted in 153 NVAF patients with CHADS2 score ≥1.The LAA was successfully occluded in 152 patients. Serious complications occurred in 5 patients. During the 12-month follow-up, ischemic stroke occurred in 2 patients, 1 patient had incomplete LAA sealing, and there was no device embolization.LAA closure with the LAmbre device shows encouraging results for stroke prevention.